For people leaving San Diego, Southwest Virginia is one of the better-value places to land. Housing and taxes cost a good deal less here, and you're right next to the Blue Ridge.
CA's top income tax rate is 12.3% versus Virginia's 5.75%, and property taxes run about 0.75% there versus roughly 1% across the region. On a $289,950 home that's a meaningful annual difference.
Cost of living & housing
Overall costs run about 39% lower here than in San Diego. It takes only about $121,379 here to match a $200,000 lifestyle there. The $289,950 median home here would run on the order of $472,390 back in San Diego.
Where to live
For a first pass, compare both the numbers and the lifestyle fit. These are useful starting points before you narrow to specific homes.
Salem is an independent city inside the Roanoke metro that still feels like a small town. It runs its own school division and takes Friday-night football seriously.